William Clark

The Treaty of Greenville was signed at Fort Greenville, Ohio, on August 3, 1795, following the Battle of Fallen Timbers.

The treaty was signed in Philadelphia by President George Washington and ratified by the Senate on December 22, 1795.

The keelboat for the expedition was built near Pittsburgh to Lewis's specifications and completed on August 31, 1803.

Lewis and his crew set sail from Pittsburgh on August 31, 1803, traveling down the Ohio River to meet Clark.

The Corps of Discovery departed Camp Dubois on May 14, 1804, under Clark's command, beginning the ascent of the Missouri River.

Sergeant Charles Floyd died on August 20, 1804, near present-day Sioux City, Iowa, marking the only death during the Lewis and Clark Expedition.

Lewis and Clark reached the Great Falls on June 13, 1805, becoming the first white men to see them.

Meriwether Lewis crossed the Continental Divide at Lemhi Pass on August 12, 1805.

The expedition sighted the Pacific Ocean on November 7, 1805, and established Fort Clatsop.

The Corps of Discovery left Fort Clatsop on March 23, 1806, after a long winter, beginning the return journey home.

The expedition reached St. Louis, Missouri, on September 23, 1806, ending the six-month return voyage.

Tribes relinquished claims to land ceded by Sac and Fox on November 3, 1804, and ceded a 20-mile strip.

The treaty was signed on August 24, 1816, at Portage des Sioux, despite being named for St. Louis.

Whaling captains Valentine Starbuck and William Clark may have sighted Malden Island in 1823, before the documented sighting by Samuel Bunker in March 1825.

Captain George Anson Byron sighted Malden Island on 30 July 1825 during the return voyage of HMS Blonde from Honolulu to London.

Two years after 1830, Catlin ascended the Missouri River over 3,000 km to Fort Union Trading Post, spending several weeks among indigenous people largely untouched by European culture.