Historedia
Episode 1 of 1

Takamine's Purification

When
1900
Where
Unspecified laboratory context
Part of
John Jacob Abel announces isolation of epinephrine

Jōkichi Takamine successfully isolated the neutral base of epinephrine in 1900, creating a more active substance.

Takamine worked with Keizo Uenaka to purify a principle 2000 times more active than Abel's epinephrine. He named it adrenaline with the formula C10H15NO3. Abel acknowledged his own efforts resulted in a derivative, not the free base.

Sources

  1. John Jacob Abel Wikipedia, revision of 2026-08-29
  2. Adrenaline Wikipedia, revision of 2026-10-05

Machine-drafted from the cited Wikipedia passages and checked by a reviewing model, not by a human editor. Every passage cites the revision it was written from; dates and places follow those passages.