Episode 1 of 2

Synthesis of Acetylsalicylic Acid

When
10 August 1897 (reported; contested)
Where
Bayer
Part of
Felix Hoffmann synthesizes acetylsalicylic acid at Bayer

Felix Hoffmann synthesized acetylsalicylic acid in pure, stable form at Bayer in 1897, with contested attribution regarding his initiative.

On 10 August 1897, Hoffmann is reported to have synthesized acetylsalicylic acid while working at Bayer, a date given by one source and contested, with some accounts placing the work earlier in August or on a different day. Sources debate whether he acted on his own initiative or under Arthur Eichengrün's instruction. Bayer later asserted the invention was due to Hoffmann, who is credited with producing the compound in a pure, stable form.

Sources

  1. Felix Hoffmann Wikipedia, revision of 2026-08-31
  2. Aspirin Wikipedia, revision of 2026-10-05

Machine-drafted from the cited Wikipedia passages and checked by a reviewing model, not by a human editor. Every passage cites the revision it was written from; dates and places follow those passages.